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isoprenoid biosynthesis

State Icon Reaction EC-Number Confidence maximal confidence score from EnzymeDetector
ATP + geranylgeranyl_phosphate <=> ADP + geranylgeranyl_diphosphate 2.7.4.B4

(2E,6E)-farnesyl_diphosphate + isopentenyl_diphosphate <=> geranylgeranyl_diphosphate + diphosphate 2.5.1
2.5.1.29 geranylgeranyl diphosphate synthase


2-phospho-4-(cytidine_5''-diphospho)-2-C-methyl-D-erythritol <=> 2-C-methyl-D-erythritol_2,4-cyclodiphosphate + CMP 4.6.1.12 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase

geranylgeranyl_diphosphate + isopentenyl_diphosphate <=> all-trans-hexaprenyl_diphosphate + diphosphate 2.5.1.82 hexaprenyl diphosphate synthase [geranylgeranyl-diphosphate specific]
2.5.1.B41


(2E,6E)-farnesyl_diphosphate + isopentenyl_diphosphate <=> di-trans,poly-cis-nonaprenyl_diphosphate + diphosphate 2.5.1.84 all-trans-nonaprenyl diphosphate synthase [geranyl-diphosphate specific]
2.5.1.85 all-trans-nonaprenyl diphosphate synthase [geranylgeranyl-diphosphate specific]
2.5.1.87 ditrans,polycis-polyprenyl diphosphate synthase [(2E,6E)-farnesyl diphosphate specific]
2.5.1.B14




(2E,6E,10E,14E)-geranylfarnesyl_diphosphate + H2O <=> ophiobolin_F + diphosphate 4.2.3.145 ophiobolin F synthase

geranylgeranyl_diphosphate <=> prephytoene_diphosphate + diphosphate 2.5.1.148 lycopaoctaene synthase
2.5.1.32 15-cis-phytoene synthase


H+ + 2-C-methyl-D-erythritol_4-phosphate + CTP <=> 4-(cytidine_5''-diphospho)-2-C-methyl-D-erythritol + diphosphate 2.7.7.60 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase

geranyl_diphosphate + isopentenyl_diphosphate <=> (2E,6E)-farnesyl_diphosphate + diphosphate 2.5.1.1 dimethylallyltranstransferase
2.5.1.10 (2E,6E)-farnesyl diphosphate synthase
2.5.1.29 geranylgeranyl diphosphate synthase



H+ + pyruvate + D-glyceraldehyde_3-phosphate <=> 1-deoxy-D-xylulose_5-phosphate + CO2 2.2.1.7 1-deoxy-D-xylulose-5-phosphate synthase

isopentenyl_diphosphate + geranylgeranyl_diphosphate <=> (2E,6E,10E,14E)-geranylfarnesyl_diphosphate + diphosphate 2.5.1.81 geranylfarnesyl diphosphate synthase
2.5.1.B41


ATP + geranylgeraniol <=> ADP + geranylgeranyl_phosphate + H+ 2.7.1.216 farnesol kinase
2.7.1.66 undecaprenol kinase
2.7.1.B19



geranylgeranyl_diphosphate + H2O <=> cyclooctat-9-en-7-ol + diphosphate 4.2.3.146 cyclooctat-9-en-7-ol synthase

2-C-methyl-D-erythritol_4-phosphate + NADP+ <=> 1-deoxy-D-xylulose_5-phosphate + NADPH + H+ 1.1.1.267 1-deoxy-D-xylulose-5-phosphate reductoisomerase

(2E,6E)-farnesyl_diphosphate + isopentenyl_diphosphate <=> di-trans-poly-cis-decaprenyl_diphosphate + diphosphate 2.5.1.87 ditrans,polycis-polyprenyl diphosphate synthase [(2E,6E)-farnesyl diphosphate specific]
2.5.1.91 all-trans-decaprenyl-diphosphate synthase


(2E,6E)-farnesyl_diphosphate + isopentenyl_diphosphate <=> all-trans-heptaprenyl_diphosphate + diphosphate 2.5.1.30 heptaprenyl diphosphate synthase
2.5.1.B41


phytyl_diphosphate + NADP+ <=> geranylgeranyl_diphosphate + NADPH + H+ 1.3.1.83 geranylgeranyl diphosphate reductase

geranyl_diphosphate + isopentenyl_diphosphate <=> nonaprenyl_diphosphate + diphosphate 2.5.1.84 all-trans-nonaprenyl diphosphate synthase [geranyl-diphosphate specific]

dimethylallyl_diphosphate + isopentenyl_diphosphate <=> geranyl_diphosphate + diphosphate 2.5.1.1 dimethylallyltranstransferase
2.5.1.10 (2E,6E)-farnesyl diphosphate synthase
2.5.1.29 geranylgeranyl diphosphate synthase
2.5.1.67 chrysanthemyl diphosphate synthase
2.5.1.69 lavandulyl diphosphate synthase





(E)-4-hydroxy-3-methylbut-2-en-1-yl_diphosphate + oxidized_ferredoxin + H2O <=> 2-C-methyl-D-erythritol_2,4-cyclodiphosphate + reduced_ferredoxin_[iron-sulfur]_cluster + H+ 1.17.7.1 (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase (ferredoxin)

geranyl_diphosphate + H2O <=> geraniol + diphosphate 3.1.7.11 geranyl diphosphate diphosphatase
3.1.7.3 monoterpenyl-diphosphatase
4.2.3.104 alpha-humulene synthase



geranylgeranyl_diphosphate + isopentenyl_diphosphate <=> nonaprenyl_diphosphate + diphosphate 2.5.1.84 all-trans-nonaprenyl diphosphate synthase [geranyl-diphosphate specific]
2.5.1.85 all-trans-nonaprenyl diphosphate synthase [geranylgeranyl-diphosphate specific]


4-(cytidine_5''-diphospho)-2-C-methyl-D-erythritol + ATP <=> H+ + 2-phospho-4-(cytidine_5''-diphospho)-2-C-methyl-D-erythritol + ADP 2.7.1.148 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase

(E)-4-hydroxy-3-methylbut-2-en-1-yl_diphosphate + NADPH <=> dimethylallyl_diphosphate + isopentenyl_diphosphate + NADP+ + H2O 1.17.7.4 4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase

geraniol + NAD+ <=> citral + NADH + H+ 1.1.1.1 alcohol dehydrogenase
1.1.1.183 geraniol dehydrogenase (NADP+)
1.1.1.198 (+)-borneol dehydrogenase
1.1.1.347 geraniol dehydrogenase (NAD+)
1.1.1.90 aryl-alcohol dehydrogenase





geranylgeranyl_diphosphate + isopentenyl_diphosphate <=> tritrans,heptacis-undecaprenyl_diphosphate + diphosphate 2.5.1.89 tritrans,polycis-undecaprenyl diphosphate synthase [geranylgeranyl-diphosphate specific]

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